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Combination blockade of KLRG1 and PD-1 promotes immune control of local and disseminated cancers

Checkpoint blockade therapy is effective against many cancers; however, new targets need to be identified to treat patients who do not respond to current treatment or demonstrate immune escape. Here, we showed that blocking the inhibitory receptor Killer cell lectin-like receptor G1 (KLRG1) enhances...

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Detalles Bibliográficos
Autores principales: Tata, Angela, Dodard, Garvin, Fugère, Céline, Leget, Corinne, Ors, Mélody, Rossi, Benjamin, Vivier, Eric, Brossay, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208121/
https://www.ncbi.nlm.nih.gov/pubmed/34188973
http://dx.doi.org/10.1080/2162402X.2021.1933808