Gastric Epithelioid Angiosarcoma: An Unexpected Tumor in an Unexpected Location

Angiosarcomas are aggressive neoplasms that arise from endothelial cells and can develop in any part of the body. Gastrointestinal angiosarcomas are very uncommon and can have a variable clinical presentation. We report a case of an 84-year-old female who presented with acute blood loss anemia. She...

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Autores principales: Sharko, Artem, Samuel, Shirly, Ying, Grace W, Prasad, Sonika, Baig, Shaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208171/
https://www.ncbi.nlm.nih.gov/pubmed/34150400
http://dx.doi.org/10.7759/cureus.15049
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author Sharko, Artem
Samuel, Shirly
Ying, Grace W
Prasad, Sonika
Baig, Shaji
author_facet Sharko, Artem
Samuel, Shirly
Ying, Grace W
Prasad, Sonika
Baig, Shaji
author_sort Sharko, Artem
collection PubMed
description Angiosarcomas are aggressive neoplasms that arise from endothelial cells and can develop in any part of the body. Gastrointestinal angiosarcomas are very uncommon and can have a variable clinical presentation. We report a case of an 84-year-old female who presented with acute blood loss anemia. She underwent a gastrointestinal workup with esophagogastroduodenoscopy (EGD), which revealed two polyps in the stomach. Histologic evaluation of the polyps was indicative of angiosarcoma, and the diagnosis was eventually confirmed by immunohistochemical analysis with positive CD31, ERG, and FLI1 stains. This case is reported to demonstrate the importance of considering angiosarcoma in the differential for patients presenting with gastrointestinal bleeding.
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spelling pubmed-82081712021-06-17 Gastric Epithelioid Angiosarcoma: An Unexpected Tumor in an Unexpected Location Sharko, Artem Samuel, Shirly Ying, Grace W Prasad, Sonika Baig, Shaji Cureus Internal Medicine Angiosarcomas are aggressive neoplasms that arise from endothelial cells and can develop in any part of the body. Gastrointestinal angiosarcomas are very uncommon and can have a variable clinical presentation. We report a case of an 84-year-old female who presented with acute blood loss anemia. She underwent a gastrointestinal workup with esophagogastroduodenoscopy (EGD), which revealed two polyps in the stomach. Histologic evaluation of the polyps was indicative of angiosarcoma, and the diagnosis was eventually confirmed by immunohistochemical analysis with positive CD31, ERG, and FLI1 stains. This case is reported to demonstrate the importance of considering angiosarcoma in the differential for patients presenting with gastrointestinal bleeding. Cureus 2021-05-15 /pmc/articles/PMC8208171/ /pubmed/34150400 http://dx.doi.org/10.7759/cureus.15049 Text en Copyright © 2021, Sharko et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Sharko, Artem
Samuel, Shirly
Ying, Grace W
Prasad, Sonika
Baig, Shaji
Gastric Epithelioid Angiosarcoma: An Unexpected Tumor in an Unexpected Location
title Gastric Epithelioid Angiosarcoma: An Unexpected Tumor in an Unexpected Location
title_full Gastric Epithelioid Angiosarcoma: An Unexpected Tumor in an Unexpected Location
title_fullStr Gastric Epithelioid Angiosarcoma: An Unexpected Tumor in an Unexpected Location
title_full_unstemmed Gastric Epithelioid Angiosarcoma: An Unexpected Tumor in an Unexpected Location
title_short Gastric Epithelioid Angiosarcoma: An Unexpected Tumor in an Unexpected Location
title_sort gastric epithelioid angiosarcoma: an unexpected tumor in an unexpected location
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208171/
https://www.ncbi.nlm.nih.gov/pubmed/34150400
http://dx.doi.org/10.7759/cureus.15049
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AT samuelshirly gastricepithelioidangiosarcomaanunexpectedtumorinanunexpectedlocation
AT yinggracew gastricepithelioidangiosarcomaanunexpectedtumorinanunexpectedlocation
AT prasadsonika gastricepithelioidangiosarcomaanunexpectedtumorinanunexpectedlocation
AT baigshaji gastricepithelioidangiosarcomaanunexpectedtumorinanunexpectedlocation

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