Type I Interferon Dependent hsa-miR-145-5p Downregulation Modulates MUC1 and TLR4 Overexpression in Salivary Glands From Sjögren’s Syndrome Patients

Sjögren’s syndrome (SS) is an autoimmune disease that mainly affects salivary glands (SG) and is characterized by overactivation of the type I interferon (IFN) pathway. Type I IFNs can decrease the levels of hsa-miR-145-5p, a miRNA with anti-inflammatory roles that is downregulated in SG from SS-pat...

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Detalles Bibliográficos
Autores principales: Jara, Daniela, Carvajal, Patricia, Castro, Isabel, Barrera, María-José, Aguilera, Sergio, González, Sergio, Molina, Claudio, Hermoso, Marcela, González, María-Julieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208490/
https://www.ncbi.nlm.nih.gov/pubmed/34149728
http://dx.doi.org/10.3389/fimmu.2021.685837

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