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The Metabolic Clock Model of B Cell Activation and Differentiation

Recent advancements in the field of B cell immunometabolism have provided mechanistic insights to B cell activation and fate determination. Here, in this short article, I will explain the main principles of our novel metabolic clock model and how it may reshape our perspective on longstanding immuno...

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Detalles Bibliográficos
Autor principal: Akkaya, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208592/
https://www.ncbi.nlm.nih.gov/pubmed/34141455
http://dx.doi.org/10.20900/immunometab20210019
Descripción
Sumario:Recent advancements in the field of B cell immunometabolism have provided mechanistic insights to B cell activation and fate determination. Here, in this short article, I will explain the main principles of our novel metabolic clock model and how it may reshape our perspective on longstanding immunological questions related to pathologies arising from out of context B cell activation.