Cargando…
Determining the parameter space for effective oxygen depletion for FLASH radiation therapy
There has been a recent revival of interest in the FLASH effect, after experiments have shown normal tissue sparing capabilities of ultra-high-dose-rate radiation with no compromise on tumour growth restraint. A model has been developed to investigate the relative importance of a number of fundament...
Autores principales: | Rothwell, B C, Kirkby, N F, Merchant, M J, Chadwick, A L, Lowe, M, Mackay, R I, Hendry, J H, Kirkby, K J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOP Publishing
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208623/ https://www.ncbi.nlm.nih.gov/pubmed/33535191 http://dx.doi.org/10.1088/1361-6560/abe2ea |
Ejemplares similares
-
Hi-C implementation of genome structure for in silico models of radiation-induced DNA damage
por: Ingram, Samuel P., et al.
Publicado: (2020) -
A phenomenological model of proton FLASH oxygen depletion effects depending on tissue vasculature and oxygen supply
por: Zou, Wei, et al.
Publicado: (2022) -
In Silico Non-Homologous End Joining Following Ion Induced DNA Double Strand Breaks Predicts That Repair Fidelity Depends on Break Density
por: Henthorn, N. T., et al.
Publicado: (2018) -
Mechanistic modelling supports entwined rather than exclusively competitive DNA double-strand break repair pathway
por: Ingram, S. P., et al.
Publicado: (2019) -
A computational approach to quantifying miscounting of radiation-induced double-strand break immunofluorescent foci
por: Ingram, Samuel P., et al.
Publicado: (2022)