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Association of UGT1A6 gene polymorphism with clinical outcome in pediatric epileptic patients on sodium valproate monotherapy

Pediatric epilepsy comprises chronic neurological disorders characterized by recurrent seizures. Sodium valproate is one of the common antiseizure medications used for treatment. Glucuronide conjugation is the major metabolic pathway of sodium valproate, carried out by the enzyme uridine 5′-diphosph...

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Detalles Bibliográficos
Autores principales: Banawalikar, N., Adiga, S., Adiga, U., Shenoy, V., Kumari, S., Shetty, P., Shetty, S., Sharmila, K.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208771/
https://www.ncbi.nlm.nih.gov/pubmed/34133540
http://dx.doi.org/10.1590/1414-431X2021e11097

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