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Smc5/6 in the rDNA modulates lifespan independently of Fob1

The ribosomal DNA (rDNA) in Saccharomyces cerevisiae is in one tandem repeat array on Chromosome XII. Two regions within each repetitive element, called intergenic spacer 1 (IGS1) and IGS2, are important for organizing the rDNA within the nucleolus. The Smc5/6 complex localizes to IGS1 and IGS2. We...

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Detalles Bibliográficos
Autores principales:	Moradi‐Fard, Sarah, Mojumdar, Aditya, Chan, Megan, Harkness, Troy A.A., Cobb, Jennifer A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208791/ https://www.ncbi.nlm.nih.gov/pubmed/33979898 http://dx.doi.org/10.1111/acel.13373

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