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Acceleration of ageing via disturbing mTOR‐regulated proteostasis by a new ageing‐associated gene PC4
Research on ageing‐associated genes is important for investigating ageing and anti‐ageing strategies. Here, we firstly reported that the human positive cofactor 4 (PC4), a multifunctional and highly conserved nucleoprotein, is accumulated and activated during ageing and causes global accelerated age...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208792/ https://www.ncbi.nlm.nih.gov/pubmed/33957702 http://dx.doi.org/10.1111/acel.13370 |