Acceleration of ageing via disturbing mTOR‐regulated proteostasis by a new ageing‐associated gene PC4

Research on ageing‐associated genes is important for investigating ageing and anti‐ageing strategies. Here, we firstly reported that the human positive cofactor 4 (PC4), a multifunctional and highly conserved nucleoprotein, is accumulated and activated during ageing and causes global accelerated age...

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Detalles Bibliográficos
Autores principales: Chen, Long, Liao, Fengying, Wu, Jie, Wang, Ziwen, Jiang, Zhongyong, Zhang, Chi, Luo, Peng, Ma, Le, Gong, Qiang, Wang, Yang, Wang, Qing, Luo, Min, Yang, Zeyu, Han, Shiqian, Shi, Chunmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208792/
https://www.ncbi.nlm.nih.gov/pubmed/33957702
http://dx.doi.org/10.1111/acel.13370

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