Sevelamer crystals—an unusual cause of large bowel obstruction

Sevelamer is a common phosphate binder used to manage hyperphosphatemia in end-stage renal disease. The medication has a well-documented gastrointestinal side-effect profile including nausea, vomiting and abdominal pain. There are few case reports of Sevelamer crystal deposition causing gastrointest...

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Detalles Bibliográficos
Autores principales: Cockrell, Hannah C, Cottrell-Cumber, Sarah, Brown, Kathryn, Murphy, Jason G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208801/
https://www.ncbi.nlm.nih.gov/pubmed/34150192
http://dx.doi.org/10.1093/jscr/rjab228
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author Cockrell, Hannah C
Cottrell-Cumber, Sarah
Brown, Kathryn
Murphy, Jason G
author_facet Cockrell, Hannah C
Cottrell-Cumber, Sarah
Brown, Kathryn
Murphy, Jason G
author_sort Cockrell, Hannah C
collection PubMed
description Sevelamer is a common phosphate binder used to manage hyperphosphatemia in end-stage renal disease. The medication has a well-documented gastrointestinal side-effect profile including nausea, vomiting and abdominal pain. There are few case reports of Sevelamer crystal deposition causing gastrointestinal mucosal injury, pseudotumor or obstruction. Here, we discuss a patient on Sevelamer who required operative management of a sigmoid obstruction. Surgical pathology showed pericolonic abscess with Sevelamer crystals.
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spelling pubmed-82088012021-06-17 Sevelamer crystals—an unusual cause of large bowel obstruction Cockrell, Hannah C Cottrell-Cumber, Sarah Brown, Kathryn Murphy, Jason G J Surg Case Rep Case Report Sevelamer is a common phosphate binder used to manage hyperphosphatemia in end-stage renal disease. The medication has a well-documented gastrointestinal side-effect profile including nausea, vomiting and abdominal pain. There are few case reports of Sevelamer crystal deposition causing gastrointestinal mucosal injury, pseudotumor or obstruction. Here, we discuss a patient on Sevelamer who required operative management of a sigmoid obstruction. Surgical pathology showed pericolonic abscess with Sevelamer crystals. Oxford University Press 2021-06-16 /pmc/articles/PMC8208801/ /pubmed/34150192 http://dx.doi.org/10.1093/jscr/rjab228 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2021. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cockrell, Hannah C
Cottrell-Cumber, Sarah
Brown, Kathryn
Murphy, Jason G
Sevelamer crystals—an unusual cause of large bowel obstruction
title Sevelamer crystals—an unusual cause of large bowel obstruction
title_full Sevelamer crystals—an unusual cause of large bowel obstruction
title_fullStr Sevelamer crystals—an unusual cause of large bowel obstruction
title_full_unstemmed Sevelamer crystals—an unusual cause of large bowel obstruction
title_short Sevelamer crystals—an unusual cause of large bowel obstruction
title_sort sevelamer crystals—an unusual cause of large bowel obstruction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208801/
https://www.ncbi.nlm.nih.gov/pubmed/34150192
http://dx.doi.org/10.1093/jscr/rjab228
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