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Reduction in mitochondrial oxidative stress mediates hypoxia-induced resistance to cisplatin in human transitional cell carcinoma cells
Tumor hypoxia is known to promote the acquisition of more aggressive phenotypes in human transitional cell carcinoma (TCC), including drug resistance. Accumulating evidence suggests that mitochondria play a central role in the chemoresistance of TCC. However, the role of mitochondria in the hypoxia-...
Autores principales: | Kim, Myung-Chul, Hwang, Sung-Hyun, Yang, Yeseul, Kim, Na-Yon, Kim, Yongbaek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208898/ https://www.ncbi.nlm.nih.gov/pubmed/34134082 http://dx.doi.org/10.1016/j.neo.2021.05.013 |
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