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Reduction in mitochondrial oxidative stress mediates hypoxia-induced resistance to cisplatin in human transitional cell carcinoma cells

Tumor hypoxia is known to promote the acquisition of more aggressive phenotypes in human transitional cell carcinoma (TCC), including drug resistance. Accumulating evidence suggests that mitochondria play a central role in the chemoresistance of TCC. However, the role of mitochondria in the hypoxia-...

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Detalles Bibliográficos
Autores principales: Kim, Myung-Chul, Hwang, Sung-Hyun, Yang, Yeseul, Kim, Na-Yon, Kim, Yongbaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208898/
https://www.ncbi.nlm.nih.gov/pubmed/34134082
http://dx.doi.org/10.1016/j.neo.2021.05.013

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