Phosphodiesterases 2, 3 and 4 can decrease cardiac effects of H(2)-histamine-receptor activation in isolated atria of transgenic mice

Histamine exerts cAMP-dependent positive inotropic effects (PIE) and positive chronotropic effects (PCE) on isolated left and right atria, respectively, of transgenic mice which overexpress the human H(2)-receptor in the heart (=H(2)-TG). To determine whether these effects are antagonized by phospho...

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Detalles Bibliográficos
Autores principales: Neumann, Joachim, Voss, Rafaela, Laufs, Ulrich, Werner, Christian, Gergs, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208929/
https://www.ncbi.nlm.nih.gov/pubmed/33576869
http://dx.doi.org/10.1007/s00210-021-02052-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208929/
https://www.ncbi.nlm.nih.gov/pubmed/33576869
http://dx.doi.org/10.1007/s00210-021-02052-y

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