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Phosphodiesterases 2, 3 and 4 can decrease cardiac effects of H(2)-histamine-receptor activation in isolated atria of transgenic mice
Histamine exerts cAMP-dependent positive inotropic effects (PIE) and positive chronotropic effects (PCE) on isolated left and right atria, respectively, of transgenic mice which overexpress the human H(2)-receptor in the heart (=H(2)-TG). To determine whether these effects are antagonized by phospho...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208929/ https://www.ncbi.nlm.nih.gov/pubmed/33576869 http://dx.doi.org/10.1007/s00210-021-02052-y |