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Pharmacological inhibition of thioredoxin reductase increases insulin secretion and diminishes beta cell viability
Apparently, both a decrease in beta cell function and in beta cell mass contribute to the progressive worsening of type 2 diabetes. So, it is of particular interest to define factors which are relevant for the regulation of insulin secretion and at the same time for the maintenance of beta cell mass...
Autores principales: | Brüning, Dennis, Hatlapatka, Kathrin, Lier-Glaubitz, Verena, Andermark, Vincent, Scherneck, Stephan, Ott, Ingo, Rustenbeck, Ingo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208932/ https://www.ncbi.nlm.nih.gov/pubmed/33464387 http://dx.doi.org/10.1007/s00210-020-02046-2 |
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