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Amitriptyline functionally antagonizes cardiac H(2) histamine receptors in transgenic mice and human atria
We have previously shown that histamine (2-(1H-imidazol-4-yl)ethanamine) exerted concentration-dependent positive inotropic effects (PIE) or positive chronotropic effects (PCE) on isolated left and right atria, respectively, of transgenic (H(2)R-TG) mice that overexpress the human H(2) histamine rec...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208937/ https://www.ncbi.nlm.nih.gov/pubmed/33625558 http://dx.doi.org/10.1007/s00210-021-02065-7 |