Cargando…
Poly(beta-amino ester) nanoparticles enable tumor-specific TRAIL secretion and a bystander effect to treat liver cancer
Despite initial promise, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based approaches to cancer treatment have yet to yield a clinically approved therapy, due to delivery challenges, a lack of potency, and drug resistance. To address these challenges, we have developed poly(beta-...
Autores principales: | Vaughan, Hannah J., Zamboni, Camila G., Radant, Nicholas P., Bhardwaj, Pranshu, Revai Lechtich, Esther, Hassan, Laboni F., Shah, Khalid, Green, Jordan J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208964/ https://www.ncbi.nlm.nih.gov/pubmed/34189258 http://dx.doi.org/10.1016/j.omto.2021.04.004 |
Ejemplares similares
-
Non-Viral Gene Delivery to Hepatocellular Carcinoma via Intra-Arterial Injection
por: Vaughan, Hannah J, et al.
Publicado: (2023) -
Polymeric nanoparticles for dual-targeted theranostic gene delivery to hepatocellular carcinoma
por: Vaughan, Hannah J., et al.
Publicado: (2022) -
Feasibility and application of machine learning enabled fast screening of poly-beta-amino-esters for cartilage therapies
por: Perni, Stefano, et al.
Publicado: (2022) -
Poly(Beta-Amino Ester) Nanoparticles Enable Nonviral Delivery of CRISPR-Cas9 Plasmids for Gene Knockout and Gene Deletion
por: Rui, Yuan, et al.
Publicado: (2020) -
Poly(Beta-Amino Ester)s as High-Yield Transfection Reagents for Recombinant Protein Production
por: Luly, Kathryn M, et al.
Publicado: (2022)