Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome

This study examined the contribution of the Apgar score at 1 and 5 min after birth to later cognitive functioning in 168 individuals with Down syndrome who were between 6 and 25 years of age at time of cognitive testing. Our results showed that a lower Apgar score at 1 min was related to a worse per...

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Autores principales: del Hoyo Soriano, Laura, Rosser, Tracie C., Hamilton, Debra R., Harvey, Danielle J., Abbeduto, Leonard, Sherman, Stephanie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208985/
https://www.ncbi.nlm.nih.gov/pubmed/34135349
http://dx.doi.org/10.1038/s41598-021-90651-3
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author del Hoyo Soriano, Laura
Rosser, Tracie C.
Hamilton, Debra R.
Harvey, Danielle J.
Abbeduto, Leonard
Sherman, Stephanie L.
author_facet del Hoyo Soriano, Laura
Rosser, Tracie C.
Hamilton, Debra R.
Harvey, Danielle J.
Abbeduto, Leonard
Sherman, Stephanie L.
author_sort del Hoyo Soriano, Laura
collection PubMed
description This study examined the contribution of the Apgar score at 1 and 5 min after birth to later cognitive functioning in 168 individuals with Down syndrome who were between 6 and 25 years of age at time of cognitive testing. Our results showed that a lower Apgar score at 1 min was related to a worse performance in later cognitive measures of receptive vocabulary, verbal comprehension and production, visual memory and working memory. Results also showed that a lower Apgar score at 5 min was only related to worse later outcomes of verbal comprehension and production and auditory working memory. Our findings suggest a need for future studies investigating how specific perinatal events reflected in the Apgar score are linked to later cognitive functioning in individuals with Down syndrome.
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spelling pubmed-82089852021-06-17 Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome del Hoyo Soriano, Laura Rosser, Tracie C. Hamilton, Debra R. Harvey, Danielle J. Abbeduto, Leonard Sherman, Stephanie L. Sci Rep Article This study examined the contribution of the Apgar score at 1 and 5 min after birth to later cognitive functioning in 168 individuals with Down syndrome who were between 6 and 25 years of age at time of cognitive testing. Our results showed that a lower Apgar score at 1 min was related to a worse performance in later cognitive measures of receptive vocabulary, verbal comprehension and production, visual memory and working memory. Results also showed that a lower Apgar score at 5 min was only related to worse later outcomes of verbal comprehension and production and auditory working memory. Our findings suggest a need for future studies investigating how specific perinatal events reflected in the Apgar score are linked to later cognitive functioning in individuals with Down syndrome. Nature Publishing Group UK 2021-06-16 /pmc/articles/PMC8208985/ /pubmed/34135349 http://dx.doi.org/10.1038/s41598-021-90651-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
del Hoyo Soriano, Laura
Rosser, Tracie C.
Hamilton, Debra R.
Harvey, Danielle J.
Abbeduto, Leonard
Sherman, Stephanie L.
Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome
title Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome
title_full Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome
title_fullStr Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome
title_full_unstemmed Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome
title_short Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome
title_sort relationship between apgar scores and long-term cognitive outcomes in individuals with down syndrome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208985/
https://www.ncbi.nlm.nih.gov/pubmed/34135349
http://dx.doi.org/10.1038/s41598-021-90651-3
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