Biochemical consequences of two clinically relevant ND-gene mutations in Escherichia coli respiratory complex I

NADH:ubiquinone oxidoreductase (respiratory complex I) plays a major role in energy metabolism by coupling electron transfer from NADH to quinone with proton translocation across the membrane. Complex I deficiencies were found to be the most common source of human mitochondrial dysfunction that mani...

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Detalles Bibliográficos
Autores principales: Nuber, Franziska, Schimpf, Johannes, di Rago, Jean-Paul, Tribouillard-Tanvier, Déborah, Procaccio, Vincent, Martin-Negrier, Marie-Laure, Trimouille, Aurélien, Biner, Olivier, von Ballmoos, Christoph, Friedrich, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209014/
https://www.ncbi.nlm.nih.gov/pubmed/34135385
http://dx.doi.org/10.1038/s41598-021-91631-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209014/
https://www.ncbi.nlm.nih.gov/pubmed/34135385
http://dx.doi.org/10.1038/s41598-021-91631-3

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