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Nanoscale spatial dependence of avidity in an IgG1 antibody

Antibodies are secreted proteins that are crucial to recognition of pathogens by the immune system and are also efficient pharmaceuticals. The affinity and specificity of target recognition can increase remarkably through avidity effects, when the antibody can bind a multivalent antigen through more...

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Detalles Bibliográficos
Autores principales: Jendroszek, Agnieszka, Kjaergaard, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209022/
https://www.ncbi.nlm.nih.gov/pubmed/34135438
http://dx.doi.org/10.1038/s41598-021-92280-2

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