Cargando…

Total femur replacement in a patient with chronic persistence osteomyelitis – A case report

INTRODUCTION AND IMPORTANCE: Total femoral replacement (TFR) is a salvage surgical procedure that has been indicated mainly for oncologic indication to avoid lower limb amputation but has recently been indicated for non-oncological disorders. CASE PRESENTATION: We report the case of a 63-year-old ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Trung, Dung Tran, Dinh, Hieu Nguyen, Le, Ngoc Thanh, Luong, Long Hoang, Nguyen, Tran Thuy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209068/
https://www.ncbi.nlm.nih.gov/pubmed/34119946
http://dx.doi.org/10.1016/j.ijscr.2021.106067
_version_ 1783709051651096576
author Trung, Dung Tran
Dinh, Hieu Nguyen
Le, Ngoc Thanh
Luong, Long Hoang
Nguyen, Tran Thuy
author_facet Trung, Dung Tran
Dinh, Hieu Nguyen
Le, Ngoc Thanh
Luong, Long Hoang
Nguyen, Tran Thuy
author_sort Trung, Dung Tran
collection PubMed
description INTRODUCTION AND IMPORTANCE: Total femoral replacement (TFR) is a salvage surgical procedure that has been indicated mainly for oncologic indication to avoid lower limb amputation but has recently been indicated for non-oncological disorders. CASE PRESENTATION: We report the case of a 63-year-old male with chronic osteomyelitis of the left femur, severe pain and bone deformation, the risk of amputation in this patient was very high. The patient underwent total femur replacement (TFR) with a modular mega-prosthesis. TFR was conducted in two phases. The first one consists of femur resection followed by placement of antibiotic cement; and the second operation was performed after 7 weeks, in which a modular mega-prosthesis was implanted. After a 2-month rehabilitation period, the patient recovered basic ambulation without any complaint of pain or detectable residual infection. The 1-year follow-up was uneventful, with no residual pain or infection. The patient retains normal ambulation and daily function. CLINICAL DISCUSSION: Chronic persistent osteomyelitis is a hard to manage non-neoplastic disorder that leads to amputation in severe cases. In such patients, TFR would be considered as a salvage therapy that could preserve the patient's anatomical integrity and ambulation. CONCLUSION: To the best of our knowledge, this is the first case of TFR for treatment of chronic persistent osteomyelitis in Vietnam. While TFR are still mainly indicated for oncology patients, TFR is anticipated to be performed more frequently for non-oncological disorders where there are extensive femoral bone loss and risk of amputation.
format Online
Article
Text
id pubmed-8209068
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-82090682021-06-23 Total femur replacement in a patient with chronic persistence osteomyelitis – A case report Trung, Dung Tran Dinh, Hieu Nguyen Le, Ngoc Thanh Luong, Long Hoang Nguyen, Tran Thuy Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Total femoral replacement (TFR) is a salvage surgical procedure that has been indicated mainly for oncologic indication to avoid lower limb amputation but has recently been indicated for non-oncological disorders. CASE PRESENTATION: We report the case of a 63-year-old male with chronic osteomyelitis of the left femur, severe pain and bone deformation, the risk of amputation in this patient was very high. The patient underwent total femur replacement (TFR) with a modular mega-prosthesis. TFR was conducted in two phases. The first one consists of femur resection followed by placement of antibiotic cement; and the second operation was performed after 7 weeks, in which a modular mega-prosthesis was implanted. After a 2-month rehabilitation period, the patient recovered basic ambulation without any complaint of pain or detectable residual infection. The 1-year follow-up was uneventful, with no residual pain or infection. The patient retains normal ambulation and daily function. CLINICAL DISCUSSION: Chronic persistent osteomyelitis is a hard to manage non-neoplastic disorder that leads to amputation in severe cases. In such patients, TFR would be considered as a salvage therapy that could preserve the patient's anatomical integrity and ambulation. CONCLUSION: To the best of our knowledge, this is the first case of TFR for treatment of chronic persistent osteomyelitis in Vietnam. While TFR are still mainly indicated for oncology patients, TFR is anticipated to be performed more frequently for non-oncological disorders where there are extensive femoral bone loss and risk of amputation. Elsevier 2021-06-09 /pmc/articles/PMC8209068/ /pubmed/34119946 http://dx.doi.org/10.1016/j.ijscr.2021.106067 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Trung, Dung Tran
Dinh, Hieu Nguyen
Le, Ngoc Thanh
Luong, Long Hoang
Nguyen, Tran Thuy
Total femur replacement in a patient with chronic persistence osteomyelitis – A case report
title Total femur replacement in a patient with chronic persistence osteomyelitis – A case report
title_full Total femur replacement in a patient with chronic persistence osteomyelitis – A case report
title_fullStr Total femur replacement in a patient with chronic persistence osteomyelitis – A case report
title_full_unstemmed Total femur replacement in a patient with chronic persistence osteomyelitis – A case report
title_short Total femur replacement in a patient with chronic persistence osteomyelitis – A case report
title_sort total femur replacement in a patient with chronic persistence osteomyelitis – a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209068/
https://www.ncbi.nlm.nih.gov/pubmed/34119946
http://dx.doi.org/10.1016/j.ijscr.2021.106067
work_keys_str_mv AT trungdungtran totalfemurreplacementinapatientwithchronicpersistenceosteomyelitisacasereport
AT dinhhieunguyen totalfemurreplacementinapatientwithchronicpersistenceosteomyelitisacasereport
AT lengocthanh totalfemurreplacementinapatientwithchronicpersistenceosteomyelitisacasereport
AT luonglonghoang totalfemurreplacementinapatientwithchronicpersistenceosteomyelitisacasereport
AT nguyentranthuy totalfemurreplacementinapatientwithchronicpersistenceosteomyelitisacasereport