Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing

Motoneuronal loss is the main feature of amyotrophic lateral sclerosis, although pathogenesis is extremely complex involving both neural and muscle cells. In order to translationally engage the sonic hedgehog pathway, which is a promising target for neural regeneration, recent studies have reported...

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Detalles Bibliográficos
Autores principales: Vicario, Nunzio, Spitale, Federica M., Tibullo, Daniele, Giallongo, Cesarina, Amorini, Angela M., Scandura, Grazia, Spoto, Graziana, Saab, Miriam W., D’Aprile, Simona, Alberghina, Cristiana, Mangione, Renata, Bernstock, Joshua D., Botta, Cirino, Gulisano, Massimo, Buratti, Emanuele, Leanza, Giampiero, Zorec, Robert, Vecchio, Michele, Di Rosa, Michelino, Li Volti, Giovanni, Lazzarino, Giuseppe, Parenti, Rosalba, Gulino, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209072/
https://www.ncbi.nlm.nih.gov/pubmed/34135312
http://dx.doi.org/10.1038/s41419-021-03907-1

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