Prophylaxis with intrathecal or high-dose methotrexate in diffuse large B-cell lymphoma and high risk of CNS relapse

Although methotrexate (MTX) is the most widely used therapy for central nervous system (CNS) prophylaxis in patients with diffuse large B-cell lymphoma (DLBCL), the optimal regimen remains unclear. We examined the efficacy of different prophylactic regimens in 585 patients with newly diagnosed DLBCL...

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Detalles Bibliográficos
Autores principales: Bobillo, Sabela, Joffe, Erel, Sermer, David, Mondello, Patrizia, Ghione, Paola, Caron, Philip C., Hamilton, Audrey, Hamlin, Paul A., Horwitz, Steven M., Kumar, Anita, Matasar, Matthew J., Batlevi, Connie L., Moskowitz, Alison, Noy, Ariela, Owens, Collette N., Palomba, M. Lia, Straus, David, von Keudell, Gottfried, Dogan, Ahmet, Zelenetz, Andrew D., Seshan, Venkatraman E., Younes, Anas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209097/
https://www.ncbi.nlm.nih.gov/pubmed/34135307
http://dx.doi.org/10.1038/s41408-021-00506-3

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