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Centrosomal P4.1-associated protein (CPAP) positively regulates endocytic vesicular transport and lysosome targeting of EGFR

Centrosomal P4.1-associated protein (CPAP) plays a critical role in restricting the centriole length in human cells. Here, we report a novel, positive regulatory influence for CPAP on endocytic vesicular transport (EVT) and lysosome targeting of internalized-cell surface receptor EGFR. We observed t...

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Detalles Bibliográficos
Autores principales: Gudi, Radhika, Palanisamy, Viswanathan, Vasu, Chenthamarakshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209166/
https://www.ncbi.nlm.nih.gov/pubmed/34135376
http://dx.doi.org/10.1038/s41598-021-91818-8