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A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma

Ultrasound cyclo plasty (UCP) is a recently developed surgical technique for glaucoma allowing a selective and controlled coagulation of the ciliary body. We herein investigated the long-term efficacy and safety of UCP for the treatment of glaucoma. This prospective study included patients with prim...

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Autores principales: Giannaccare, Giuseppe, Pellegrini, Marco, Bernabei, Federico, Urbini, Lara, Bergamini, Fulvio, Ferro Desideri, Lorenzo, Bagnis, Alessandro, Biagini, Francesco, Cassottana, Paola, Del Noce, Chiara, Carnevali, Adriano, Scorcia, Vincenzo, Traverso, Carlo E., Vagge, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209230/
https://www.ncbi.nlm.nih.gov/pubmed/34135447
http://dx.doi.org/10.1038/s41598-021-92233-9
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author Giannaccare, Giuseppe
Pellegrini, Marco
Bernabei, Federico
Urbini, Lara
Bergamini, Fulvio
Ferro Desideri, Lorenzo
Bagnis, Alessandro
Biagini, Francesco
Cassottana, Paola
Del Noce, Chiara
Carnevali, Adriano
Scorcia, Vincenzo
Traverso, Carlo E.
Vagge, Aldo
author_facet Giannaccare, Giuseppe
Pellegrini, Marco
Bernabei, Federico
Urbini, Lara
Bergamini, Fulvio
Ferro Desideri, Lorenzo
Bagnis, Alessandro
Biagini, Francesco
Cassottana, Paola
Del Noce, Chiara
Carnevali, Adriano
Scorcia, Vincenzo
Traverso, Carlo E.
Vagge, Aldo
author_sort Giannaccare, Giuseppe
collection PubMed
description Ultrasound cyclo plasty (UCP) is a recently developed surgical technique for glaucoma allowing a selective and controlled coagulation of the ciliary body. We herein investigated the long-term efficacy and safety of UCP for the treatment of glaucoma. This prospective study included patients with primary and secondary glaucoma. All surgeries were performed using the EyeOP1 device (Eye Tech Care, Rillieux-la-Pape, France). Sixty-six patients were included, and 60 completed regularly the 2-year follow-up. Preoperative IOP was 28.5 ± 9.6 mmHg and significantly decreased to 17.0 ± 5.4 at 2 years (p < 0.001). The daily number of both hypotensive eye drops and acetazolamide tablets decreased significantly (respectively, from 2.6 ± 1.1 to 1.7 ± 1.2 and from 0.7 ± 0.8 to 0.2 ± 0.5; both p < 0.001). At 2 years, 68.1% of patients met the definition of qualified success (IOP < 21 mmHg regardless of glaucoma medications) and 10.3% of patients met the definition of complete success (IOP < 21 mmHg without glaucoma medications). No major intra- or postoperative complications occurred; however, 15 eyes required additional glaucoma surgery. These results suggest that UCP is an effective and safe procedure to reduce IOP in glaucoma patients through a 2-year follow-up period.
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spelling pubmed-82092302021-06-17 A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma Giannaccare, Giuseppe Pellegrini, Marco Bernabei, Federico Urbini, Lara Bergamini, Fulvio Ferro Desideri, Lorenzo Bagnis, Alessandro Biagini, Francesco Cassottana, Paola Del Noce, Chiara Carnevali, Adriano Scorcia, Vincenzo Traverso, Carlo E. Vagge, Aldo Sci Rep Article Ultrasound cyclo plasty (UCP) is a recently developed surgical technique for glaucoma allowing a selective and controlled coagulation of the ciliary body. We herein investigated the long-term efficacy and safety of UCP for the treatment of glaucoma. This prospective study included patients with primary and secondary glaucoma. All surgeries were performed using the EyeOP1 device (Eye Tech Care, Rillieux-la-Pape, France). Sixty-six patients were included, and 60 completed regularly the 2-year follow-up. Preoperative IOP was 28.5 ± 9.6 mmHg and significantly decreased to 17.0 ± 5.4 at 2 years (p < 0.001). The daily number of both hypotensive eye drops and acetazolamide tablets decreased significantly (respectively, from 2.6 ± 1.1 to 1.7 ± 1.2 and from 0.7 ± 0.8 to 0.2 ± 0.5; both p < 0.001). At 2 years, 68.1% of patients met the definition of qualified success (IOP < 21 mmHg regardless of glaucoma medications) and 10.3% of patients met the definition of complete success (IOP < 21 mmHg without glaucoma medications). No major intra- or postoperative complications occurred; however, 15 eyes required additional glaucoma surgery. These results suggest that UCP is an effective and safe procedure to reduce IOP in glaucoma patients through a 2-year follow-up period. Nature Publishing Group UK 2021-06-16 /pmc/articles/PMC8209230/ /pubmed/34135447 http://dx.doi.org/10.1038/s41598-021-92233-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Giannaccare, Giuseppe
Pellegrini, Marco
Bernabei, Federico
Urbini, Lara
Bergamini, Fulvio
Ferro Desideri, Lorenzo
Bagnis, Alessandro
Biagini, Francesco
Cassottana, Paola
Del Noce, Chiara
Carnevali, Adriano
Scorcia, Vincenzo
Traverso, Carlo E.
Vagge, Aldo
A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_full A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_fullStr A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_full_unstemmed A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_short A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_sort 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209230/
https://www.ncbi.nlm.nih.gov/pubmed/34135447
http://dx.doi.org/10.1038/s41598-021-92233-9
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