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Fitness selection in human pluripotent stem cells and interspecies chimeras: Implications for human development and regenerative medicine
A small number of pluripotent cells within early embryo gives rise to all cells in the adult body, including germ cells. Hence, any mutations occurring in the pluripotent cell population are at risk of being propagated to their daughter cells and could lead to congenital defects or embryonic lethali...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209287/ https://www.ncbi.nlm.nih.gov/pubmed/33891964 http://dx.doi.org/10.1016/j.ydbio.2021.03.025 |