Innate Signaling in the CNS Prevents Demyelination in a Focal EAE Model

The pathological hallmark of multiple sclerosis (MS) is the formation of multifocal demyelinating lesions in the central nervous system (CNS). Stimulation of innate receptors has been shown to suppress experimental autoimmune encephalomyelitis (EAE), an MS-like disease in mice. Specifically, targeti...

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Detalles Bibliográficos
Autores principales: Dubik, Magdalena, Marczynska, Joanna, Mørch, Marlene T., Webster, Gill, Jensen, Kirstine Nolling, Wlodarczyk, Agnieszka, Khorooshi, Reza, Owens, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209300/
https://www.ncbi.nlm.nih.gov/pubmed/34149350
http://dx.doi.org/10.3389/fnins.2021.682451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209300/
https://www.ncbi.nlm.nih.gov/pubmed/34149350
http://dx.doi.org/10.3389/fnins.2021.682451

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