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Innate Signaling in the CNS Prevents Demyelination in a Focal EAE Model
The pathological hallmark of multiple sclerosis (MS) is the formation of multifocal demyelinating lesions in the central nervous system (CNS). Stimulation of innate receptors has been shown to suppress experimental autoimmune encephalomyelitis (EAE), an MS-like disease in mice. Specifically, targeti...
Autores principales: | Dubik, Magdalena, Marczynska, Joanna, Mørch, Marlene T., Webster, Gill, Jensen, Kirstine Nolling, Wlodarczyk, Agnieszka, Khorooshi, Reza, Owens, Trevor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209300/ https://www.ncbi.nlm.nih.gov/pubmed/34149350 http://dx.doi.org/10.3389/fnins.2021.682451 |
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