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Focused Ultrasound Ablation of an Arteriovenous Malformation Model

Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one...

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Detalles Bibliográficos
Autores principales: Jones, Jesse, Bolding, Mark, Ullman, Henrik, Kaneko, Naoki, Tateshima, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209376/
https://www.ncbi.nlm.nih.gov/pubmed/34149602
http://dx.doi.org/10.3389/fneur.2021.671380
Descripción
Sumario:Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one session of ultrasound gradually reduced flow through the lesion without inducing rupture. Due to its non-invasive yet immediate ablative effects, focused ultrasound may allow safer treatment of AVMs. However, further studies are needed to clarify its efficacy and side effect profile.