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Focused Ultrasound Ablation of an Arteriovenous Malformation Model

Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one...

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Autores principales: Jones, Jesse, Bolding, Mark, Ullman, Henrik, Kaneko, Naoki, Tateshima, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209376/
https://www.ncbi.nlm.nih.gov/pubmed/34149602
http://dx.doi.org/10.3389/fneur.2021.671380
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author Jones, Jesse
Bolding, Mark
Ullman, Henrik
Kaneko, Naoki
Tateshima, Satoshi
author_facet Jones, Jesse
Bolding, Mark
Ullman, Henrik
Kaneko, Naoki
Tateshima, Satoshi
author_sort Jones, Jesse
collection PubMed
description Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one session of ultrasound gradually reduced flow through the lesion without inducing rupture. Due to its non-invasive yet immediate ablative effects, focused ultrasound may allow safer treatment of AVMs. However, further studies are needed to clarify its efficacy and side effect profile.
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spelling pubmed-82093762021-06-18 Focused Ultrasound Ablation of an Arteriovenous Malformation Model Jones, Jesse Bolding, Mark Ullman, Henrik Kaneko, Naoki Tateshima, Satoshi Front Neurol Neurology Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one session of ultrasound gradually reduced flow through the lesion without inducing rupture. Due to its non-invasive yet immediate ablative effects, focused ultrasound may allow safer treatment of AVMs. However, further studies are needed to clarify its efficacy and side effect profile. Frontiers Media S.A. 2021-06-03 /pmc/articles/PMC8209376/ /pubmed/34149602 http://dx.doi.org/10.3389/fneur.2021.671380 Text en Copyright © 2021 Jones, Bolding, Ullman, Kaneko and Tateshima. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Jones, Jesse
Bolding, Mark
Ullman, Henrik
Kaneko, Naoki
Tateshima, Satoshi
Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_full Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_fullStr Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_full_unstemmed Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_short Focused Ultrasound Ablation of an Arteriovenous Malformation Model
title_sort focused ultrasound ablation of an arteriovenous malformation model
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209376/
https://www.ncbi.nlm.nih.gov/pubmed/34149602
http://dx.doi.org/10.3389/fneur.2021.671380
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