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Focused Ultrasound Ablation of an Arteriovenous Malformation Model
Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209376/ https://www.ncbi.nlm.nih.gov/pubmed/34149602 http://dx.doi.org/10.3389/fneur.2021.671380 |
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author | Jones, Jesse Bolding, Mark Ullman, Henrik Kaneko, Naoki Tateshima, Satoshi |
author_facet | Jones, Jesse Bolding, Mark Ullman, Henrik Kaneko, Naoki Tateshima, Satoshi |
author_sort | Jones, Jesse |
collection | PubMed |
description | Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one session of ultrasound gradually reduced flow through the lesion without inducing rupture. Due to its non-invasive yet immediate ablative effects, focused ultrasound may allow safer treatment of AVMs. However, further studies are needed to clarify its efficacy and side effect profile. |
format | Online Article Text |
id | pubmed-8209376 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82093762021-06-18 Focused Ultrasound Ablation of an Arteriovenous Malformation Model Jones, Jesse Bolding, Mark Ullman, Henrik Kaneko, Naoki Tateshima, Satoshi Front Neurol Neurology Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one session of ultrasound gradually reduced flow through the lesion without inducing rupture. Due to its non-invasive yet immediate ablative effects, focused ultrasound may allow safer treatment of AVMs. However, further studies are needed to clarify its efficacy and side effect profile. Frontiers Media S.A. 2021-06-03 /pmc/articles/PMC8209376/ /pubmed/34149602 http://dx.doi.org/10.3389/fneur.2021.671380 Text en Copyright © 2021 Jones, Bolding, Ullman, Kaneko and Tateshima. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Jones, Jesse Bolding, Mark Ullman, Henrik Kaneko, Naoki Tateshima, Satoshi Focused Ultrasound Ablation of an Arteriovenous Malformation Model |
title | Focused Ultrasound Ablation of an Arteriovenous Malformation Model |
title_full | Focused Ultrasound Ablation of an Arteriovenous Malformation Model |
title_fullStr | Focused Ultrasound Ablation of an Arteriovenous Malformation Model |
title_full_unstemmed | Focused Ultrasound Ablation of an Arteriovenous Malformation Model |
title_short | Focused Ultrasound Ablation of an Arteriovenous Malformation Model |
title_sort | focused ultrasound ablation of an arteriovenous malformation model |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209376/ https://www.ncbi.nlm.nih.gov/pubmed/34149602 http://dx.doi.org/10.3389/fneur.2021.671380 |
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