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ALKBH1-8 and FTO: Potential Therapeutic Targets and Prognostic Biomarkers in Lung Adenocarcinoma Pathogenesis
The AlkB family consists of Fe(II)- and α-ketoglutarate-dependent dioxygenases that can catalyze demethylation on a variety of substrates, such as RNA and DNA, subsequently affecting tumor progression and prognosis. However, their detailed functional roles in lung adenocarcinoma (LUAD) have not been...
Autores principales: | Wu, Geting, Yan, Yuanliang, Cai, Yuan, Peng, Bi, Li, Juanni, Huang, Jinzhou, Xu, Zhijie, Zhou, Jianhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209387/ https://www.ncbi.nlm.nih.gov/pubmed/34150745 http://dx.doi.org/10.3389/fcell.2021.633927 |
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