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3,3’-Diindolylmethane Enhances Paclitaxel Sensitivity by Suppressing DNMT1-Mediated KLF4 Methylation in Breast Cancer

Paclitaxel (PTX) is a first-line chemotherapeutic drug for the treatment of breast cancer, but drug resistance seriously limits its clinical use. The aim of the present work was to explore the effect of 3,3’-diindolylmethane (DIM) on PTX sensitivity and its possible mechanism in breast cancer. The e...

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Detalles Bibliográficos
Autores principales:	Xiang, Fenfen, Zhu, Zhaowei, Zhang, Mengzhe, Wang, Jie, Chen, Zixi, Li, Xiaoxiao, Zhang, Tao, Gu, Qing, Wu, Rong, Kang, Xiangdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209418/ https://www.ncbi.nlm.nih.gov/pubmed/34150611 http://dx.doi.org/10.3389/fonc.2021.627856

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