Axotomy Induces Drp1-Dependent Fragmentation of Axonal Mitochondria

It is well established that CNS axons fail to regenerate, undergo retrograde dieback, and form dystrophic growth cones due to both intrinsic and extrinsic factors. We sought to investigate the role of axonal mitochondria in the axonal response to injury. A viral vector (AAV) containing a mitochondri...

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Detalles Bibliográficos
Autores principales: Kedra, Joseph, Lin, Shen, Pacheco, Almudena, Gallo, Gianluca, Smith, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209475/
https://www.ncbi.nlm.nih.gov/pubmed/34149354
http://dx.doi.org/10.3389/fnmol.2021.668670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209475/
https://www.ncbi.nlm.nih.gov/pubmed/34149354
http://dx.doi.org/10.3389/fnmol.2021.668670

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