Cargando…
Amyloid-β Impairs Dendritic Trafficking of Golgi-Like Organelles in the Early Phase Preceding Neurite Atrophy: Rescue by Mirtazapine
Neurite atrophy with loss of neuronal polarity is a pathological hallmark of Alzheimer’s disease (AD) and other neurological disorders. While there is substantial agreement that disruption of intracellular vesicle trafficking is associated with axonal pathology in AD, comparatively less is known reg...
Autores principales: | Fabbretti, Elsa, Antognolli, Giulia, Tongiorgi, Enrico |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209480/ https://www.ncbi.nlm.nih.gov/pubmed/34149353 http://dx.doi.org/10.3389/fnmol.2021.661728 |
Ejemplares similares
-
Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice
por: Bittolo, Tamara, et al.
Publicado: (2016) -
Distinct role of 5′UTR sequences in dendritic trafficking of BDNF mRNA: additional mechanisms for the BDNF splice variants spatial code
por: Colliva, Andrea, et al.
Publicado: (2021) -
Impact of neurite alignment on organelle motion
por: Mytiliniou, Maria, et al.
Publicado: (2022) -
Protective role of mirtazapine in adult female Mecp2(+/−) mice and patients with Rett syndrome
por: Flores Gutiérrez, Javier, et al.
Publicado: (2020) -
In vitro modeling of dendritic atrophy in Rett syndrome: determinants for phenotypic drug screening in neurodevelopmental disorders
por: Nerli, Elisa, et al.
Publicado: (2020)