An integrative analysis of genome-wide 5-hydroxymethylcytosines in circulating cell-free DNA detects noninvasive diagnostic markers for gliomas

BACKGROUND: Gliomas, especially the high-grade glioblastomas (GBM), are highly aggressive tumors in the central nervous system (CNS) with dismal clinical outcomes. Effective biomarkers, which are not currently available, may improve clinical outcomes through early detection. We sought to develop a n...

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Detalles Bibliográficos
Autores principales: Cai, Jiajun, Zeng, Chang, Hua, Wei, Qi, Zengxin, Song, Yanqun, Lu, Xingyu, Li, Dongdong, Zhang, Zhou, Cui, Xiaolong, Zhang, Xin, Yang, Zixiao, Zhang, Jinsen, Quan, Kai, Zhu, Wei, Cai, Jiabin, He, Chuan, Cheng, Shi-Yuan, Zhang, Wei, Mao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209591/
https://www.ncbi.nlm.nih.gov/pubmed/34151267
http://dx.doi.org/10.1093/noajnl/vdab049

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