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Aquarium: open-source laboratory software for design, execution and data management

Automation has been shown to improve the replicability and scalability of biomedical and bioindustrial research. Although the work performed in many labs is repetitive and can be standardized, few academic labs can afford the time and money required to automate their workflows with robotics. We prop...

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Autores principales: Vrana, Justin, de Lange, Orlando, Yang, Yaoyu, Newman, Garrett, Saleem, Ayesha, Miller, Abraham, Cordray, Cameron, Halabiya, Samer, Parks, Michelle, Lopez, Eriberto, Goldberg, Sarah, Keller, Benjamin, Strickland, Devin, Klavins, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209617/
https://www.ncbi.nlm.nih.gov/pubmed/34151028
http://dx.doi.org/10.1093/synbio/ysab006
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author Vrana, Justin
de Lange, Orlando
Yang, Yaoyu
Newman, Garrett
Saleem, Ayesha
Miller, Abraham
Cordray, Cameron
Halabiya, Samer
Parks, Michelle
Lopez, Eriberto
Goldberg, Sarah
Keller, Benjamin
Strickland, Devin
Klavins, Eric
author_facet Vrana, Justin
de Lange, Orlando
Yang, Yaoyu
Newman, Garrett
Saleem, Ayesha
Miller, Abraham
Cordray, Cameron
Halabiya, Samer
Parks, Michelle
Lopez, Eriberto
Goldberg, Sarah
Keller, Benjamin
Strickland, Devin
Klavins, Eric
author_sort Vrana, Justin
collection PubMed
description Automation has been shown to improve the replicability and scalability of biomedical and bioindustrial research. Although the work performed in many labs is repetitive and can be standardized, few academic labs can afford the time and money required to automate their workflows with robotics. We propose that human-in-the-loop automation can fill this critical gap. To this end, we present Aquarium, an open-source, web-based software application that integrates experimental design, inventory management, protocol execution and data capture. We provide a high-level view of how researchers can install Aquarium and use it in their own labs. We discuss the impacts of the Aquarium on working practices, use in biofoundries and opportunities it affords for collaboration and education in life science laboratory research and manufacture.
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spelling pubmed-82096172021-06-17 Aquarium: open-source laboratory software for design, execution and data management Vrana, Justin de Lange, Orlando Yang, Yaoyu Newman, Garrett Saleem, Ayesha Miller, Abraham Cordray, Cameron Halabiya, Samer Parks, Michelle Lopez, Eriberto Goldberg, Sarah Keller, Benjamin Strickland, Devin Klavins, Eric Synth Biol (Oxf) Software Automation has been shown to improve the replicability and scalability of biomedical and bioindustrial research. Although the work performed in many labs is repetitive and can be standardized, few academic labs can afford the time and money required to automate their workflows with robotics. We propose that human-in-the-loop automation can fill this critical gap. To this end, we present Aquarium, an open-source, web-based software application that integrates experimental design, inventory management, protocol execution and data capture. We provide a high-level view of how researchers can install Aquarium and use it in their own labs. We discuss the impacts of the Aquarium on working practices, use in biofoundries and opportunities it affords for collaboration and education in life science laboratory research and manufacture. Oxford University Press 2021-01-30 /pmc/articles/PMC8209617/ /pubmed/34151028 http://dx.doi.org/10.1093/synbio/ysab006 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Software
Vrana, Justin
de Lange, Orlando
Yang, Yaoyu
Newman, Garrett
Saleem, Ayesha
Miller, Abraham
Cordray, Cameron
Halabiya, Samer
Parks, Michelle
Lopez, Eriberto
Goldberg, Sarah
Keller, Benjamin
Strickland, Devin
Klavins, Eric
Aquarium: open-source laboratory software for design, execution and data management
title Aquarium: open-source laboratory software for design, execution and data management
title_full Aquarium: open-source laboratory software for design, execution and data management
title_fullStr Aquarium: open-source laboratory software for design, execution and data management
title_full_unstemmed Aquarium: open-source laboratory software for design, execution and data management
title_short Aquarium: open-source laboratory software for design, execution and data management
title_sort aquarium: open-source laboratory software for design, execution and data management
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209617/
https://www.ncbi.nlm.nih.gov/pubmed/34151028
http://dx.doi.org/10.1093/synbio/ysab006
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