Cargando…
Aquarium: open-source laboratory software for design, execution and data management
Automation has been shown to improve the replicability and scalability of biomedical and bioindustrial research. Although the work performed in many labs is repetitive and can be standardized, few academic labs can afford the time and money required to automate their workflows with robotics. We prop...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209617/ https://www.ncbi.nlm.nih.gov/pubmed/34151028 http://dx.doi.org/10.1093/synbio/ysab006 |
_version_ | 1783709164353093632 |
---|---|
author | Vrana, Justin de Lange, Orlando Yang, Yaoyu Newman, Garrett Saleem, Ayesha Miller, Abraham Cordray, Cameron Halabiya, Samer Parks, Michelle Lopez, Eriberto Goldberg, Sarah Keller, Benjamin Strickland, Devin Klavins, Eric |
author_facet | Vrana, Justin de Lange, Orlando Yang, Yaoyu Newman, Garrett Saleem, Ayesha Miller, Abraham Cordray, Cameron Halabiya, Samer Parks, Michelle Lopez, Eriberto Goldberg, Sarah Keller, Benjamin Strickland, Devin Klavins, Eric |
author_sort | Vrana, Justin |
collection | PubMed |
description | Automation has been shown to improve the replicability and scalability of biomedical and bioindustrial research. Although the work performed in many labs is repetitive and can be standardized, few academic labs can afford the time and money required to automate their workflows with robotics. We propose that human-in-the-loop automation can fill this critical gap. To this end, we present Aquarium, an open-source, web-based software application that integrates experimental design, inventory management, protocol execution and data capture. We provide a high-level view of how researchers can install Aquarium and use it in their own labs. We discuss the impacts of the Aquarium on working practices, use in biofoundries and opportunities it affords for collaboration and education in life science laboratory research and manufacture. |
format | Online Article Text |
id | pubmed-8209617 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-82096172021-06-17 Aquarium: open-source laboratory software for design, execution and data management Vrana, Justin de Lange, Orlando Yang, Yaoyu Newman, Garrett Saleem, Ayesha Miller, Abraham Cordray, Cameron Halabiya, Samer Parks, Michelle Lopez, Eriberto Goldberg, Sarah Keller, Benjamin Strickland, Devin Klavins, Eric Synth Biol (Oxf) Software Automation has been shown to improve the replicability and scalability of biomedical and bioindustrial research. Although the work performed in many labs is repetitive and can be standardized, few academic labs can afford the time and money required to automate their workflows with robotics. We propose that human-in-the-loop automation can fill this critical gap. To this end, we present Aquarium, an open-source, web-based software application that integrates experimental design, inventory management, protocol execution and data capture. We provide a high-level view of how researchers can install Aquarium and use it in their own labs. We discuss the impacts of the Aquarium on working practices, use in biofoundries and opportunities it affords for collaboration and education in life science laboratory research and manufacture. Oxford University Press 2021-01-30 /pmc/articles/PMC8209617/ /pubmed/34151028 http://dx.doi.org/10.1093/synbio/ysab006 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Software Vrana, Justin de Lange, Orlando Yang, Yaoyu Newman, Garrett Saleem, Ayesha Miller, Abraham Cordray, Cameron Halabiya, Samer Parks, Michelle Lopez, Eriberto Goldberg, Sarah Keller, Benjamin Strickland, Devin Klavins, Eric Aquarium: open-source laboratory software for design, execution and data management |
title | Aquarium: open-source laboratory software for design, execution and data management |
title_full | Aquarium: open-source laboratory software for design, execution and data management |
title_fullStr | Aquarium: open-source laboratory software for design, execution and data management |
title_full_unstemmed | Aquarium: open-source laboratory software for design, execution and data management |
title_short | Aquarium: open-source laboratory software for design, execution and data management |
title_sort | aquarium: open-source laboratory software for design, execution and data management |
topic | Software |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209617/ https://www.ncbi.nlm.nih.gov/pubmed/34151028 http://dx.doi.org/10.1093/synbio/ysab006 |
work_keys_str_mv | AT vranajustin aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT delangeorlando aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT yangyaoyu aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT newmangarrett aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT saleemayesha aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT millerabraham aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT cordraycameron aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT halabiyasamer aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT parksmichelle aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT lopezeriberto aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT goldbergsarah aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT kellerbenjamin aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT stricklanddevin aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement AT klavinseric aquariumopensourcelaboratorysoftwarefordesignexecutionanddatamanagement |