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Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population
The pks island codes for the enzymes necessary for synthesis of the genotoxin colibactin, which contributes to the virulence of Escherichia coli strains and is suspected of promoting colorectal cancer. From a collection of 785 human and bovine E. coli isolates, we identified 109 strains carrying a h...
Autores principales: | Auvray, Frédéric, Perrat, Alexandre, Arimizu, Yoko, Chagneau, Camille V., Bossuet-Greif, Nadège, Massip, Clémence, Brugère, Hubert, Nougayrède, Jean-Philippe, Hayashi, Tetsuya, Branchu, Priscilla, Ogura, Yoshitoshi, Oswald, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209727/ https://www.ncbi.nlm.nih.gov/pubmed/33961542 http://dx.doi.org/10.1099/mgen.0.000579 |
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