Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance

Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the...

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Autores principales: Stenhouse, George E., Jere, Khuzwayo C., Peno, Chikondi, Bengtsson, Rebecca J., Chinyama, End, Mandolo, Jonathan, Cain, Amy, Iturriza-Gómara, Miren, Bar-Zeev, Naor, Cunliffe, Nigel A., Cornick, Jennifer, Baker, Kate S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209728/
https://www.ncbi.nlm.nih.gov/pubmed/33945457
http://dx.doi.org/10.1099/mgen.0.000532
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author Stenhouse, George E.
Jere, Khuzwayo C.
Peno, Chikondi
Bengtsson, Rebecca J.
Chinyama, End
Mandolo, Jonathan
Cain, Amy
Iturriza-Gómara, Miren
Bar-Zeev, Naor
Cunliffe, Nigel A.
Cornick, Jennifer
Baker, Kate S.
author_facet Stenhouse, George E.
Jere, Khuzwayo C.
Peno, Chikondi
Bengtsson, Rebecca J.
Chinyama, End
Mandolo, Jonathan
Cain, Amy
Iturriza-Gómara, Miren
Bar-Zeev, Naor
Cunliffe, Nigel A.
Cornick, Jennifer
Baker, Kate S.
author_sort Stenhouse, George E.
collection PubMed
description Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1.
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spelling pubmed-82097282021-06-17 Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance Stenhouse, George E. Jere, Khuzwayo C. Peno, Chikondi Bengtsson, Rebecca J. Chinyama, End Mandolo, Jonathan Cain, Amy Iturriza-Gómara, Miren Bar-Zeev, Naor Cunliffe, Nigel A. Cornick, Jennifer Baker, Kate S. Microb Genom Short Communications Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1. Microbiology Society 2021-05-04 /pmc/articles/PMC8209728/ /pubmed/33945457 http://dx.doi.org/10.1099/mgen.0.000532 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
spellingShingle Short Communications
Stenhouse, George E.
Jere, Khuzwayo C.
Peno, Chikondi
Bengtsson, Rebecca J.
Chinyama, End
Mandolo, Jonathan
Cain, Amy
Iturriza-Gómara, Miren
Bar-Zeev, Naor
Cunliffe, Nigel A.
Cornick, Jennifer
Baker, Kate S.
Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance
title Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance
title_full Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance
title_fullStr Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance
title_full_unstemmed Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance
title_short Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance
title_sort whole genome sequence analysis of shigella from malawi identifies fluoroquinolone resistance
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209728/
https://www.ncbi.nlm.nih.gov/pubmed/33945457
http://dx.doi.org/10.1099/mgen.0.000532
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