Stabilization of an (211)At-Labeled Antibody with Sodium Ascorbate

[Image: see text] (211)At, an α-particle emitter, has recently attracted attention for radioimmunotherapy of intractable cancers. However, our sodium dodecyl sulfate polyacrylamide gel electrophoresis and flow cytometry analyses revealed that (211)At-labeled immunoconjugates are easily disrupted. Lu...

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Detalles Bibliográficos
Autores principales: Manabe, Shino, Takashima, Hiroki, Ohnuki, Kazunobu, Koga, Yoshikatsu, Tsumura, Ryo, Iwata, Nozomi, Wang, Yang, Yokokita, Takuya, Komori, Yukiko, Usuda, Sachiko, Mori, Daiki, Haba, Hiromitsu, Fujii, Hirofumi, Yasunaga, Masahiro, Matsumura, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209801/
https://www.ncbi.nlm.nih.gov/pubmed/34151070
http://dx.doi.org/10.1021/acsomega.1c00684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209801/
https://www.ncbi.nlm.nih.gov/pubmed/34151070
http://dx.doi.org/10.1021/acsomega.1c00684

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