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Constructing a gnotobiotic mouse model with a synthetic human gut microbiome to study host–microbe cross talk
Reproducible in vivo models are necessary to address functional aspects of the gut microbiome in various diseases. Here, we present a gnotobiotic mouse model that allows for the investigation of specific microbial functions within the microbiome. We describe how to culture 14 different well-characte...
Autores principales: | Steimle, Alex, De Sciscio, Alessandro, Neumann, Mareike, Grant, Erica T., Pereira, Gabriel V., Ohno, Hiroshi, Martens, Eric C., Desai, Mahesh S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209845/ https://www.ncbi.nlm.nih.gov/pubmed/34179836 http://dx.doi.org/10.1016/j.xpro.2021.100607 |
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