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Japanese rapid/living recommendations on drug management for COVID‐19
The coronavirus disease (COVID‐19) has spread worldwide since early 2020, and there are still no signs of resolution. The Japanese Clinical Practice Guidelines for the Management of Sepsis and Septic Shock (J‐SSCG) 2020 Special Committee created the Japanese rapid/living recommendations on drug mana...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209876/ https://www.ncbi.nlm.nih.gov/pubmed/34178358 http://dx.doi.org/10.1002/ams2.664 |
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author | Yamakawa, Kazuma Yamamoto, Ryo Ishimaru, Go Hashimoto, Hideki Terayama, Takero Hara, Yoshitaka Hasegawa, Daisuke Ishihara, Tadashi Imura, Haruki Okano, Hiromu Narita, Chihiro Mayumi, Takuya Yasuda, Hideto Yamada, Kohei Yamada, Hiroyuki Kawasaki, Tatsuya Shime, Nobuaki Doi, Kent Egi, Moritoki Ogura, Hiroshi Aihara, Morio Tanaka, Hiroshi Nishida, Osamu |
author_facet | Yamakawa, Kazuma Yamamoto, Ryo Ishimaru, Go Hashimoto, Hideki Terayama, Takero Hara, Yoshitaka Hasegawa, Daisuke Ishihara, Tadashi Imura, Haruki Okano, Hiromu Narita, Chihiro Mayumi, Takuya Yasuda, Hideto Yamada, Kohei Yamada, Hiroyuki Kawasaki, Tatsuya Shime, Nobuaki Doi, Kent Egi, Moritoki Ogura, Hiroshi Aihara, Morio Tanaka, Hiroshi Nishida, Osamu |
author_sort | Yamakawa, Kazuma |
collection | PubMed |
description | The coronavirus disease (COVID‐19) has spread worldwide since early 2020, and there are still no signs of resolution. The Japanese Clinical Practice Guidelines for the Management of Sepsis and Septic Shock (J‐SSCG) 2020 Special Committee created the Japanese rapid/living recommendations on drug management for COVID‐19 using the experience of creating the J‐SSCGs. The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach was used to determine the certainty of the evidence and strength of the recommendations. The first edition of this guideline was released on 9 September, 2020, and this document is the revised edition (version 3.1) (released 30 March, 2021). Clinical questions (CQs) were set for the following seven drugs: favipiravir (CQ1), remdesivir (CQ2), hydroxychloroquine (CQ3), corticosteroids (CQ4), tocilizumab (CQ5), ciclesonide (CQ6), and anticoagulants (CQ7). Favipiravir is recommended for patients with mild COVID‐19 not requiring supplemental oxygen (GRADE 2C); remdesivir for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 2B). Hydroxychloroquine is not recommended for all COVID‐19 patients (GRADE 1B). Corticosteroids are recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 1B) and severe COVID‐19 patients requiring ventilator management/intensive care (GRADE 1A); however, their use is not recommended for mild COVID‐19 patients not requiring supplemental oxygen (GRADE 1B). Tocilizumab is recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 2B). Anticoagulant therapy is recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization and severe COVID‐19 patients requiring ventilator management/intensive care (GRADE 2C). We hope that these clinical practice guidelines will aid medical professionals involved in the care of COVID‐19 patients. |
format | Online Article Text |
id | pubmed-8209876 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82098762021-06-21 Japanese rapid/living recommendations on drug management for COVID‐19 Yamakawa, Kazuma Yamamoto, Ryo Ishimaru, Go Hashimoto, Hideki Terayama, Takero Hara, Yoshitaka Hasegawa, Daisuke Ishihara, Tadashi Imura, Haruki Okano, Hiromu Narita, Chihiro Mayumi, Takuya Yasuda, Hideto Yamada, Kohei Yamada, Hiroyuki Kawasaki, Tatsuya Shime, Nobuaki Doi, Kent Egi, Moritoki Ogura, Hiroshi Aihara, Morio Tanaka, Hiroshi Nishida, Osamu Acute Med Surg Original Articles The coronavirus disease (COVID‐19) has spread worldwide since early 2020, and there are still no signs of resolution. The Japanese Clinical Practice Guidelines for the Management of Sepsis and Septic Shock (J‐SSCG) 2020 Special Committee created the Japanese rapid/living recommendations on drug management for COVID‐19 using the experience of creating the J‐SSCGs. The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach was used to determine the certainty of the evidence and strength of the recommendations. The first edition of this guideline was released on 9 September, 2020, and this document is the revised edition (version 3.1) (released 30 March, 2021). Clinical questions (CQs) were set for the following seven drugs: favipiravir (CQ1), remdesivir (CQ2), hydroxychloroquine (CQ3), corticosteroids (CQ4), tocilizumab (CQ5), ciclesonide (CQ6), and anticoagulants (CQ7). Favipiravir is recommended for patients with mild COVID‐19 not requiring supplemental oxygen (GRADE 2C); remdesivir for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 2B). Hydroxychloroquine is not recommended for all COVID‐19 patients (GRADE 1B). Corticosteroids are recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 1B) and severe COVID‐19 patients requiring ventilator management/intensive care (GRADE 1A); however, their use is not recommended for mild COVID‐19 patients not requiring supplemental oxygen (GRADE 1B). Tocilizumab is recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 2B). Anticoagulant therapy is recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization and severe COVID‐19 patients requiring ventilator management/intensive care (GRADE 2C). We hope that these clinical practice guidelines will aid medical professionals involved in the care of COVID‐19 patients. John Wiley and Sons Inc. 2021-07-12 /pmc/articles/PMC8209876/ /pubmed/34178358 http://dx.doi.org/10.1002/ams2.664 Text en © 2021 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Yamakawa, Kazuma Yamamoto, Ryo Ishimaru, Go Hashimoto, Hideki Terayama, Takero Hara, Yoshitaka Hasegawa, Daisuke Ishihara, Tadashi Imura, Haruki Okano, Hiromu Narita, Chihiro Mayumi, Takuya Yasuda, Hideto Yamada, Kohei Yamada, Hiroyuki Kawasaki, Tatsuya Shime, Nobuaki Doi, Kent Egi, Moritoki Ogura, Hiroshi Aihara, Morio Tanaka, Hiroshi Nishida, Osamu Japanese rapid/living recommendations on drug management for COVID‐19 |
title | Japanese rapid/living recommendations on drug management for COVID‐19 |
title_full | Japanese rapid/living recommendations on drug management for COVID‐19 |
title_fullStr | Japanese rapid/living recommendations on drug management for COVID‐19 |
title_full_unstemmed | Japanese rapid/living recommendations on drug management for COVID‐19 |
title_short | Japanese rapid/living recommendations on drug management for COVID‐19 |
title_sort | japanese rapid/living recommendations on drug management for covid‐19 |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209876/ https://www.ncbi.nlm.nih.gov/pubmed/34178358 http://dx.doi.org/10.1002/ams2.664 |
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