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Japanese rapid/living recommendations on drug management for COVID‐19

The coronavirus disease (COVID‐19) has spread worldwide since early 2020, and there are still no signs of resolution. The Japanese Clinical Practice Guidelines for the Management of Sepsis and Septic Shock (J‐SSCG) 2020 Special Committee created the Japanese rapid/living recommendations on drug mana...

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Autores principales: Yamakawa, Kazuma, Yamamoto, Ryo, Ishimaru, Go, Hashimoto, Hideki, Terayama, Takero, Hara, Yoshitaka, Hasegawa, Daisuke, Ishihara, Tadashi, Imura, Haruki, Okano, Hiromu, Narita, Chihiro, Mayumi, Takuya, Yasuda, Hideto, Yamada, Kohei, Yamada, Hiroyuki, Kawasaki, Tatsuya, Shime, Nobuaki, Doi, Kent, Egi, Moritoki, Ogura, Hiroshi, Aihara, Morio, Tanaka, Hiroshi, Nishida, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209876/
https://www.ncbi.nlm.nih.gov/pubmed/34178358
http://dx.doi.org/10.1002/ams2.664
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author Yamakawa, Kazuma
Yamamoto, Ryo
Ishimaru, Go
Hashimoto, Hideki
Terayama, Takero
Hara, Yoshitaka
Hasegawa, Daisuke
Ishihara, Tadashi
Imura, Haruki
Okano, Hiromu
Narita, Chihiro
Mayumi, Takuya
Yasuda, Hideto
Yamada, Kohei
Yamada, Hiroyuki
Kawasaki, Tatsuya
Shime, Nobuaki
Doi, Kent
Egi, Moritoki
Ogura, Hiroshi
Aihara, Morio
Tanaka, Hiroshi
Nishida, Osamu
author_facet Yamakawa, Kazuma
Yamamoto, Ryo
Ishimaru, Go
Hashimoto, Hideki
Terayama, Takero
Hara, Yoshitaka
Hasegawa, Daisuke
Ishihara, Tadashi
Imura, Haruki
Okano, Hiromu
Narita, Chihiro
Mayumi, Takuya
Yasuda, Hideto
Yamada, Kohei
Yamada, Hiroyuki
Kawasaki, Tatsuya
Shime, Nobuaki
Doi, Kent
Egi, Moritoki
Ogura, Hiroshi
Aihara, Morio
Tanaka, Hiroshi
Nishida, Osamu
author_sort Yamakawa, Kazuma
collection PubMed
description The coronavirus disease (COVID‐19) has spread worldwide since early 2020, and there are still no signs of resolution. The Japanese Clinical Practice Guidelines for the Management of Sepsis and Septic Shock (J‐SSCG) 2020 Special Committee created the Japanese rapid/living recommendations on drug management for COVID‐19 using the experience of creating the J‐SSCGs. The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach was used to determine the certainty of the evidence and strength of the recommendations. The first edition of this guideline was released on 9 September, 2020, and this document is the revised edition (version 3.1) (released 30 March, 2021). Clinical questions (CQs) were set for the following seven drugs: favipiravir (CQ1), remdesivir (CQ2), hydroxychloroquine (CQ3), corticosteroids (CQ4), tocilizumab (CQ5), ciclesonide (CQ6), and anticoagulants (CQ7). Favipiravir is recommended for patients with mild COVID‐19 not requiring supplemental oxygen (GRADE 2C); remdesivir for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 2B). Hydroxychloroquine is not recommended for all COVID‐19 patients (GRADE 1B). Corticosteroids are recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 1B) and severe COVID‐19 patients requiring ventilator management/intensive care (GRADE 1A); however, their use is not recommended for mild COVID‐19 patients not requiring supplemental oxygen (GRADE 1B). Tocilizumab is recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 2B). Anticoagulant therapy is recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization and severe COVID‐19 patients requiring ventilator management/intensive care (GRADE 2C). We hope that these clinical practice guidelines will aid medical professionals involved in the care of COVID‐19 patients.
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spelling pubmed-82098762021-06-21 Japanese rapid/living recommendations on drug management for COVID‐19 Yamakawa, Kazuma Yamamoto, Ryo Ishimaru, Go Hashimoto, Hideki Terayama, Takero Hara, Yoshitaka Hasegawa, Daisuke Ishihara, Tadashi Imura, Haruki Okano, Hiromu Narita, Chihiro Mayumi, Takuya Yasuda, Hideto Yamada, Kohei Yamada, Hiroyuki Kawasaki, Tatsuya Shime, Nobuaki Doi, Kent Egi, Moritoki Ogura, Hiroshi Aihara, Morio Tanaka, Hiroshi Nishida, Osamu Acute Med Surg Original Articles The coronavirus disease (COVID‐19) has spread worldwide since early 2020, and there are still no signs of resolution. The Japanese Clinical Practice Guidelines for the Management of Sepsis and Septic Shock (J‐SSCG) 2020 Special Committee created the Japanese rapid/living recommendations on drug management for COVID‐19 using the experience of creating the J‐SSCGs. The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach was used to determine the certainty of the evidence and strength of the recommendations. The first edition of this guideline was released on 9 September, 2020, and this document is the revised edition (version 3.1) (released 30 March, 2021). Clinical questions (CQs) were set for the following seven drugs: favipiravir (CQ1), remdesivir (CQ2), hydroxychloroquine (CQ3), corticosteroids (CQ4), tocilizumab (CQ5), ciclesonide (CQ6), and anticoagulants (CQ7). Favipiravir is recommended for patients with mild COVID‐19 not requiring supplemental oxygen (GRADE 2C); remdesivir for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 2B). Hydroxychloroquine is not recommended for all COVID‐19 patients (GRADE 1B). Corticosteroids are recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 1B) and severe COVID‐19 patients requiring ventilator management/intensive care (GRADE 1A); however, their use is not recommended for mild COVID‐19 patients not requiring supplemental oxygen (GRADE 1B). Tocilizumab is recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization (GRADE 2B). Anticoagulant therapy is recommended for moderate COVID‐19 patients requiring supplemental oxygen/hospitalization and severe COVID‐19 patients requiring ventilator management/intensive care (GRADE 2C). We hope that these clinical practice guidelines will aid medical professionals involved in the care of COVID‐19 patients. John Wiley and Sons Inc. 2021-07-12 /pmc/articles/PMC8209876/ /pubmed/34178358 http://dx.doi.org/10.1002/ams2.664 Text en © 2021 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Yamakawa, Kazuma
Yamamoto, Ryo
Ishimaru, Go
Hashimoto, Hideki
Terayama, Takero
Hara, Yoshitaka
Hasegawa, Daisuke
Ishihara, Tadashi
Imura, Haruki
Okano, Hiromu
Narita, Chihiro
Mayumi, Takuya
Yasuda, Hideto
Yamada, Kohei
Yamada, Hiroyuki
Kawasaki, Tatsuya
Shime, Nobuaki
Doi, Kent
Egi, Moritoki
Ogura, Hiroshi
Aihara, Morio
Tanaka, Hiroshi
Nishida, Osamu
Japanese rapid/living recommendations on drug management for COVID‐19
title Japanese rapid/living recommendations on drug management for COVID‐19
title_full Japanese rapid/living recommendations on drug management for COVID‐19
title_fullStr Japanese rapid/living recommendations on drug management for COVID‐19
title_full_unstemmed Japanese rapid/living recommendations on drug management for COVID‐19
title_short Japanese rapid/living recommendations on drug management for COVID‐19
title_sort japanese rapid/living recommendations on drug management for covid‐19
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8209876/
https://www.ncbi.nlm.nih.gov/pubmed/34178358
http://dx.doi.org/10.1002/ams2.664
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