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Public knowledge, attitudes and practices surrounding antibiotic use and resistance in Cambodia

BACKGROUND: WHO’s Global Action Plan on Antimicrobial Resistance includes as a priority to increase public education surrounding antibiotic use and resistance. Monitoring population-level antibiotic behaviours is crucial for informing intervention strategies, but data from a broad range of settings,...

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Autores principales: Lim, Jane Mingjie, Chhoun, Pheak, Tuot, Sovannary, Om, Chhorvoin, Krang, Sidonn, Ly, Sovann, Hsu, Li Yang, Yi, Siyan, Tam, Clarence C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210153/
https://www.ncbi.nlm.nih.gov/pubmed/34223067
http://dx.doi.org/10.1093/jacamr/dlaa115
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author Lim, Jane Mingjie
Chhoun, Pheak
Tuot, Sovannary
Om, Chhorvoin
Krang, Sidonn
Ly, Sovann
Hsu, Li Yang
Yi, Siyan
Tam, Clarence C
author_facet Lim, Jane Mingjie
Chhoun, Pheak
Tuot, Sovannary
Om, Chhorvoin
Krang, Sidonn
Ly, Sovann
Hsu, Li Yang
Yi, Siyan
Tam, Clarence C
author_sort Lim, Jane Mingjie
collection PubMed
description BACKGROUND: WHO’s Global Action Plan on Antimicrobial Resistance includes as a priority to increase public education surrounding antibiotic use and resistance. Monitoring population-level antibiotic behaviours is crucial for informing intervention strategies, but data from a broad range of settings, particularly lower-resourced countries, are lacking. OBJECTIVES: We measured public knowledge, attitudes and practices regarding antibiotics and antibiotic resistance in Cambodia, providing baseline information against which to monitor the progress of future interventions. METHODS: Between September and October 2018, we conducted a household survey of knowledge, attitudes and practices related to antibiotic use in urban and rural populations of three Cambodian provinces: Phnom Penh, Siem Reap and Prey Veng. Response rates were respectively 79%, 86% and 86%. RESULTS: Among the 2005 participants, we found high levels of awareness of terms relating to antibiotics (86.5%) and antibiotic resistance; most participants also recognized that antibiotic resistance is a problem (58.4%). However, few understood that antibiotics are effective only against bacterial infections (1.2%). We also found province-specific differences in participants’ sources of antibiotics and their sources of AMR-related information. In regression analyses, more favourable antibiotic practice scores were associated with higher knowledge (β = 0.18; 95% CI: 0.14–0.22) and attitude (β = 0.16; 95% CI: 0.11–0.22) scores, as well as trust in healthcare sources to obtain antibiotics and antibiotic information. CONCLUSIONS: This study highlights the importance of interventions and public communication on antibiotic use and resistance that is effectively targeted to the local context through trusted healthcare providers.
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spelling pubmed-82101532021-07-02 Public knowledge, attitudes and practices surrounding antibiotic use and resistance in Cambodia Lim, Jane Mingjie Chhoun, Pheak Tuot, Sovannary Om, Chhorvoin Krang, Sidonn Ly, Sovann Hsu, Li Yang Yi, Siyan Tam, Clarence C JAC Antimicrob Resist Original Article BACKGROUND: WHO’s Global Action Plan on Antimicrobial Resistance includes as a priority to increase public education surrounding antibiotic use and resistance. Monitoring population-level antibiotic behaviours is crucial for informing intervention strategies, but data from a broad range of settings, particularly lower-resourced countries, are lacking. OBJECTIVES: We measured public knowledge, attitudes and practices regarding antibiotics and antibiotic resistance in Cambodia, providing baseline information against which to monitor the progress of future interventions. METHODS: Between September and October 2018, we conducted a household survey of knowledge, attitudes and practices related to antibiotic use in urban and rural populations of three Cambodian provinces: Phnom Penh, Siem Reap and Prey Veng. Response rates were respectively 79%, 86% and 86%. RESULTS: Among the 2005 participants, we found high levels of awareness of terms relating to antibiotics (86.5%) and antibiotic resistance; most participants also recognized that antibiotic resistance is a problem (58.4%). However, few understood that antibiotics are effective only against bacterial infections (1.2%). We also found province-specific differences in participants’ sources of antibiotics and their sources of AMR-related information. In regression analyses, more favourable antibiotic practice scores were associated with higher knowledge (β = 0.18; 95% CI: 0.14–0.22) and attitude (β = 0.16; 95% CI: 0.11–0.22) scores, as well as trust in healthcare sources to obtain antibiotics and antibiotic information. CONCLUSIONS: This study highlights the importance of interventions and public communication on antibiotic use and resistance that is effectively targeted to the local context through trusted healthcare providers. Oxford University Press 2021-02-03 /pmc/articles/PMC8210153/ /pubmed/34223067 http://dx.doi.org/10.1093/jacamr/dlaa115 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Article
Lim, Jane Mingjie
Chhoun, Pheak
Tuot, Sovannary
Om, Chhorvoin
Krang, Sidonn
Ly, Sovann
Hsu, Li Yang
Yi, Siyan
Tam, Clarence C
Public knowledge, attitudes and practices surrounding antibiotic use and resistance in Cambodia
title Public knowledge, attitudes and practices surrounding antibiotic use and resistance in Cambodia
title_full Public knowledge, attitudes and practices surrounding antibiotic use and resistance in Cambodia
title_fullStr Public knowledge, attitudes and practices surrounding antibiotic use and resistance in Cambodia
title_full_unstemmed Public knowledge, attitudes and practices surrounding antibiotic use and resistance in Cambodia
title_short Public knowledge, attitudes and practices surrounding antibiotic use and resistance in Cambodia
title_sort public knowledge, attitudes and practices surrounding antibiotic use and resistance in cambodia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210153/
https://www.ncbi.nlm.nih.gov/pubmed/34223067
http://dx.doi.org/10.1093/jacamr/dlaa115
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