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Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma

Glioblastoma (GBM) is the most common and aggressive intrinsic brain tumour in adults. Epigenetic mechanisms controlling normal brain development are often dysregulated in GBM. Among these, BMI1, a structural component of the Polycomb Repressive Complex 1 (PRC1), which promotes the H2AK119ub catalyt...

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Detalles Bibliográficos
Autores principales:	Freire-Benéitez, Verónica, Pomella, Nicola, Millner, Thomas O, Dumas, Anaëlle A, Niklison-Chirou, Maria Victoria, Maniati, Eleni, Wang, Jun, Rajeeve, Vinothini, Cutillas, Pedro, Marino, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Cancer Gene Regulation, Chromatin, and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210184/ https://www.ncbi.nlm.nih.gov/pubmed/34316702 http://dx.doi.org/10.1093/narcan/zcab009

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