Cargando…

Replication protein A: a multifunctional protein with roles in DNA replication, repair and beyond

Single-stranded DNA (ssDNA) forms continuously during DNA replication and is an important intermediate during recombination-mediated repair of damaged DNA. Replication protein A (RPA) is the major eukaryotic ssDNA-binding protein. As such, RPA protects the transiently formed ssDNA from nucleolytic d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dueva, Rositsa, Iliakis, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Critical Reviews and Perspectives
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210275/ https://www.ncbi.nlm.nih.gov/pubmed/34316690 http://dx.doi.org/10.1093/narcan/zcaa022

Ejemplares similares

Unbalanced Growth, the DNA Replication Cycle and Discovery of Repair Replication
por: Hanawalt, Philip C.
Publicado: (2023)

Chemical Inhibition of RPA by HAMNO Alters Cell Cycle Dynamics by Impeding DNA Replication and G2-to-M Transition but Has Little Effect on the Radiation-Induced DNA Damage Response
por: Dueva, Rositsa, et al.
Publicado: (2023)

Competition for DNA binding between the genome protector replication protein A and the genome modifying APOBEC3 single-stranded DNA deaminases
por: Wong, Lai, et al.
Publicado: (2022)

Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G(2)-phase
por: Mladenov, Emil, et al.
Publicado: (2019)

The Roles of Bacterial DNA Double-Strand Break Repair Proteins in Chromosomal DNA Replication
por: Sinha, Anurag Kumar, et al.
Publicado: (2020)

Shift in G(1)-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation
por: Li, Fanghua, et al.
Publicado: (2021)

DNA mismatch repair in cancer immunotherapy
por: Guan, Junhong, et al.
Publicado: (2023)

Dynamic binding of replication protein a is required for DNA repair
por: Chen, Ran, et al.
Publicado: (2016)

What is replication?
por: Nosek, Brian A., et al.
Publicado: (2020)

On the road to replication
por: Diffley, John FX
Publicado: (2016)

Beyond Trust: Plagiarism and Truth
por: Penders, Bart
Publicado: (2017)

Werner Syndrome Protein and DNA Replication
por: Mukherjee, Shibani, et al.
Publicado: (2018)

Mechanisms of Post-Replication DNA Repair
por: Gao, Yanzhe, et al.
Publicado: (2017)

Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers
por: Bhaskara, Srividya
Publicado: (2015)

Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication
por: Aklilu, Behailu B., et al.
Publicado: (2014)

Depletion of HIF-1α by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia
por: Hamidi, Akram, et al.
Publicado: (2022)

DNA binding by polycomb-group proteins: searching for the link to CpG islands
por: Owen, Brady M, et al.
Publicado: (2022)

Essential functions of iron-requiring proteins in DNA replication, repair and cell cycle control
por: Zhang, Caiguo
Publicado: (2014)

SMC5/6: Multifunctional Player in Replication
por: Palecek, Jan J.
Publicado: (2018)

Prp43/DHX15 exemplify RNA helicase multifunctionality in the gene expression network
por: Bohnsack, Katherine E, et al.
Publicado: (2022)

Increased Resection at DSBs in G(2)-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ
por: Xiao, Huaping, et al.
Publicado: (2022)

Genealogy, Virality, and Potentiality: Moving Beyond Orientalism with COVID-19
por: Kirksey, Eben
Publicado: (2021)

The Different Faces of Rolling-Circle Replication and Its Multifunctional Initiator Proteins
por: Wawrzyniak, Paweł, et al.
Publicado: (2017)

β-CASP proteins removing RNA polymerase from DNA: when a torpedo is needed to shoot a sitting duck
por: Wiedermannová, Jana, et al.
Publicado: (2021)

Slowing Replication in Preparation for Reduction
por: Lawrence, Katherine S., et al.
Publicado: (2012)

Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication
por: Martinez, Matthew P., et al.
Publicado: (2017)

Multifunctional Protein A Is the Only Viral Protein Required for Nodavirus RNA Replication Crown Formation
por: den Boon, Johan A., et al.
Publicado: (2022)

The Werner syndrome protein: linking the replication checkpoint response to genome stability
por: Pichierri, Pietro, et al.
Publicado: (2011)

Central Role of Ubiquitination in Genome Maintenance: DNA Replication and Damage Repair
por: Ghosh, Soma, et al.
Publicado: (2012)

DNA Polymerase Gamma in Mitochondrial DNA Replication and Repair
por: Copeland, William C., et al.
Publicado: (2003)

Genetic instability is prevented by Mrc1-dependent spatio-temporal separation of replicative and repair activities of homologous recombination: Homologous recombination tolerates replicative stress by Mrc1-regulated replication and repair activities operating at S and G2 in distinct subnuclear compartments
por: Prado, Félix
Publicado: (2014)

Travels with ubiquitin: from protein degradation to DNA repair
por: Jentsch, Stefan
Publicado: (2011)

Maneuvers on PCNA Rings during DNA Replication and Repair
por: Slade, Dea
Publicado: (2018)

The tRNA identity landscape for aminoacylation and beyond
por: Giegé, Richard, et al.
Publicado: (2023)

Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA
por: Gueranger, Quentin, et al.
Publicado: (2011)

Mechanisms and Regulation of DNA-Protein Crosslink Repair During DNA Replication by SPRTN Protease
por: Perry, Megan, et al.
Publicado: (2022)

Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells
por: Arakawa, Hiroshi, et al.
Publicado: (2012)

The multifunctional protein CI of potyviruses plays interlinked and distinct roles in viral genome replication and intercellular movement
por: Deng, Ping, et al.
Publicado: (2015)

DNA translocation activity of the multifunctional replication protein ORF904 from the archaeal plasmid pRN1
por: Sanchez, Martin, et al.
Publicado: (2009)

DNA polymerase ζ in DNA replication and repair
por: Martin, Sara K, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_gkt304mj29ftddpvks2rb2pmcp