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Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis

Accumulating evidence suggests that the root of drug chemoresistance in breast cancer is tightly associated with subpopulations of cancer stem cells (CSCs), whose activation is largely dependent on taxol-promoting autophagy. Our pilot study identified GRP78 as a specific marker for chemoresistance p...

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Detalles Bibliográficos
Autores principales: Liao, Mianmian, Wang, Caiwei, Yang, Bowen, Huang, Danping, Zheng, Yifeng, Wang, Shengqi, Wang, Xuan, Zhang, Juping, Tang, Chunbian, Xu, Zheng, He, Yu, Huang, Ruolin, Zhang, Fengxue, Wang, Zhiyu, Wang, Neng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210424/
https://www.ncbi.nlm.nih.gov/pubmed/34149413
http://dx.doi.org/10.3389/fphar.2021.659297