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Application of fluorescent dextrans to the brain surface under constant pressure reveals AQP4-independent solute uptake
Extracellular solutes in the central nervous system are exchanged between the interstitial fluid, the perivascular compartment, and the cerebrospinal fluid (CSF). The “glymphatic” mechanism proposes that the astrocyte water channel aquaporin-4 (AQP4) is a major determinant of solute transport betwee...
Autores principales: | Smith, Alex J., Akdemir, Gokhan, Wadhwa, Meetu, Song, Dan, Verkman, Alan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210582/ https://www.ncbi.nlm.nih.gov/pubmed/34128962 http://dx.doi.org/10.1085/jgp.202112898 |
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