Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19

Our understanding of protective versus pathological immune responses to SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of patients at the extremes of the disease severity spectrum. Here, we performed multi-omic single-cell immune profiling o...

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Detalles Bibliográficos
Autores principales: Wilk, Aaron J., Lee, Madeline J., Wei, Bei, Parks, Benjamin, Pi, Ruoxi, Martínez-Colón, Giovanny J., Ranganath, Thanmayi, Zhao, Nancy Q., Taylor, Shalina, Becker, Winston, Jimenez-Morales, David, Blomkalns, Andra L., O’Hara, Ruth, Ashley, Euan A., Nadeau, Kari C., Yang, Samuel, Holmes, Susan, Rabinovitch, Marlene, Rogers, Angela J., Greenleaf, William J., Blish, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210586/
https://www.ncbi.nlm.nih.gov/pubmed/34128959
http://dx.doi.org/10.1084/jem.20210582

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