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Demalonylation of DDX3 by Sirtuin 5 promotes antiviral innate immune responses

Rationale: Hosts defend against viral infection by sensing viral pathogen-associated molecular patterns and activating antiviral innate immunity through TBK1-IRF3 signaling. However, the underlying molecular mechanism remains unclear. Methods: SiRNAs targeting Sirt1-7 were transfected into macrophag...

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Detalles Bibliográficos
Autores principales:	He, Xingying, Li, Tianliang, Qin, Kewei, Luo, Shiyuan, Li, Zhenjie, Ji, Qingqing, Song, Honghao, He, Huyang, Tang, Hao, Han, Chaofeng, Li, Hongjiao, Luo, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210596/ https://www.ncbi.nlm.nih.gov/pubmed/34158847 http://dx.doi.org/10.7150/thno.52934

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