Major vault protein (MVP) negatively regulates osteoclastogenesis via calcineurin-NFATc1 pathway inhibition

Rationale: Bone homeostasis is maintained by a balanced interplay of osteoblasts and osteoclasts. Osteoclasts are derived from monocyte/macrophage lineage. Major vault protein (MVP) is known to promote apoptosis and prevent metabolic diseases in macrophage. However, whether MVP is involved in osteoc...

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Detalles Bibliográficos
Autores principales: Yuan, Lichan, Zhao, Na, Wang, Junyi, Liu, Yuying, Meng, Li, Guo, Shuyu, Wiemer, Erik A.C., Chen, Qi, Mao, Yelin, Ben, Jingjing, Ma, Junqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210610/
https://www.ncbi.nlm.nih.gov/pubmed/34158848
http://dx.doi.org/10.7150/thno.58468

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