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Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer’s disease
It is currently unclear how amyloid-β and tau deposition are linked to changes in synaptic function and axonal structure over the course of Alzheimer’s disease. Here, we assessed these relationships by measuring presynaptic (synaptosomal-associated protein 25, SNAP25; growth-associated protein 43, G...
Autores principales: | Pereira, Joana B, Janelidze, Shorena, Ossenkoppele, Rik, Kvartsberg, Hlin, Brinkmalm, Ann, Mattsson-Carlgren, Niklas, Stomrud, Erik, Smith, Ruben, Zetterberg, Henrik, Blennow, Kaj, Hansson, Oskar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210638/ https://www.ncbi.nlm.nih.gov/pubmed/33279949 http://dx.doi.org/10.1093/brain/awaa395 |
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