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The prevalence of diabetes amongst young Emirati female adults in the United Arab Emirates: A cross-sectional study

AIMS: The prevalence of type 2 diabetes is rapidly increasing in the United Arab Emirates (UAE). The purpose of this study was to investigate the prevalence of prediabetes and diabetes using FPG and HbA1c and to examine their relationships with obesity and other risk factors in young female Emirati...

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Autores principales: Mohamad, Maysm N., Ismail, Leila Cheikh, Stojanovska, Lily, Apostolopoulos, Vasso, Feehan, Jack, Jarrar, Amjad H., Al Dhaheri, Ayesha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211155/
https://www.ncbi.nlm.nih.gov/pubmed/34138882
http://dx.doi.org/10.1371/journal.pone.0252884
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author Mohamad, Maysm N.
Ismail, Leila Cheikh
Stojanovska, Lily
Apostolopoulos, Vasso
Feehan, Jack
Jarrar, Amjad H.
Al Dhaheri, Ayesha S.
author_facet Mohamad, Maysm N.
Ismail, Leila Cheikh
Stojanovska, Lily
Apostolopoulos, Vasso
Feehan, Jack
Jarrar, Amjad H.
Al Dhaheri, Ayesha S.
author_sort Mohamad, Maysm N.
collection PubMed
description AIMS: The prevalence of type 2 diabetes is rapidly increasing in the United Arab Emirates (UAE). The purpose of this study was to investigate the prevalence of prediabetes and diabetes using FPG and HbA1c and to examine their relationships with obesity and other risk factors in young female Emirati college students. METHODS: In this cross-sectional study we recruited 555 female college students aged 17–25, enrolled at United Arab Emirates University in Al Ain, UAE. Anthropometric analysis, blood pressure, and various biochemical markers were measured using standard methods. Type 2 Diabetes, impaired fasting plasma glucose (FPG), and elevated HbA1c levels were examined in the study population as per the standards of medical care in diabetes, set out by the American Diabetes Association in 2020. RESULTS: Based on the HbA1c test, the prevalence of pre-diabetes and diabetes were 24% and 8.6%, respectively. Based on the FPG test, the prevalence of pre-diabetes and diabetes were 9.2% and 0.5%, respectively. The kappa statistic of concordance between HbA1c and FPG was 0.287, P < 0.001. Abnormal glycemic status was significantly associated with decreased high-density lipoprotein (HDL) level (< 50 mg/dl) (p = 0.002) and elevated high-sensitivity C-reactive protein (Hs-CRP) level (≥ 2.0 mg/L) (P < 0.001). CONCLUSIONS: Using FPG to evaluate glycemic control seems to underestimate the burden of undiagnosed diabetes which could have a significant impact on clinical practice. Our data indicates an association between abnormal glycemic status with HDL and Hs-CRP. Further evaluation is needed to assess the impact of using HbA1c as a diagnostic test for diabetes in the UAE.
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spelling pubmed-82111552021-06-29 The prevalence of diabetes amongst young Emirati female adults in the United Arab Emirates: A cross-sectional study Mohamad, Maysm N. Ismail, Leila Cheikh Stojanovska, Lily Apostolopoulos, Vasso Feehan, Jack Jarrar, Amjad H. Al Dhaheri, Ayesha S. PLoS One Research Article AIMS: The prevalence of type 2 diabetes is rapidly increasing in the United Arab Emirates (UAE). The purpose of this study was to investigate the prevalence of prediabetes and diabetes using FPG and HbA1c and to examine their relationships with obesity and other risk factors in young female Emirati college students. METHODS: In this cross-sectional study we recruited 555 female college students aged 17–25, enrolled at United Arab Emirates University in Al Ain, UAE. Anthropometric analysis, blood pressure, and various biochemical markers were measured using standard methods. Type 2 Diabetes, impaired fasting plasma glucose (FPG), and elevated HbA1c levels were examined in the study population as per the standards of medical care in diabetes, set out by the American Diabetes Association in 2020. RESULTS: Based on the HbA1c test, the prevalence of pre-diabetes and diabetes were 24% and 8.6%, respectively. Based on the FPG test, the prevalence of pre-diabetes and diabetes were 9.2% and 0.5%, respectively. The kappa statistic of concordance between HbA1c and FPG was 0.287, P < 0.001. Abnormal glycemic status was significantly associated with decreased high-density lipoprotein (HDL) level (< 50 mg/dl) (p = 0.002) and elevated high-sensitivity C-reactive protein (Hs-CRP) level (≥ 2.0 mg/L) (P < 0.001). CONCLUSIONS: Using FPG to evaluate glycemic control seems to underestimate the burden of undiagnosed diabetes which could have a significant impact on clinical practice. Our data indicates an association between abnormal glycemic status with HDL and Hs-CRP. Further evaluation is needed to assess the impact of using HbA1c as a diagnostic test for diabetes in the UAE. Public Library of Science 2021-06-17 /pmc/articles/PMC8211155/ /pubmed/34138882 http://dx.doi.org/10.1371/journal.pone.0252884 Text en © 2021 Mohamad et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Mohamad, Maysm N.
Ismail, Leila Cheikh
Stojanovska, Lily
Apostolopoulos, Vasso
Feehan, Jack
Jarrar, Amjad H.
Al Dhaheri, Ayesha S.
The prevalence of diabetes amongst young Emirati female adults in the United Arab Emirates: A cross-sectional study
title The prevalence of diabetes amongst young Emirati female adults in the United Arab Emirates: A cross-sectional study
title_full The prevalence of diabetes amongst young Emirati female adults in the United Arab Emirates: A cross-sectional study
title_fullStr The prevalence of diabetes amongst young Emirati female adults in the United Arab Emirates: A cross-sectional study
title_full_unstemmed The prevalence of diabetes amongst young Emirati female adults in the United Arab Emirates: A cross-sectional study
title_short The prevalence of diabetes amongst young Emirati female adults in the United Arab Emirates: A cross-sectional study
title_sort prevalence of diabetes amongst young emirati female adults in the united arab emirates: a cross-sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211155/
https://www.ncbi.nlm.nih.gov/pubmed/34138882
http://dx.doi.org/10.1371/journal.pone.0252884
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